R packages by medianasoft

MedianaDesigner - Power and Sample Size Calculations for Clinical Trials

Efficient simulation-based power and sample size calculations are supported for a broad class of late-stage clinical trials. The following modules are included in the package: Adaptive designs with data-driven sample size or event count re-estimation, Adaptive designs with data-driven treatment selection, Adaptive designs with data-driven population selection, Optimal selection of a futility stopping rule, Event prediction in event-driven trials, Adaptive trials with response-adaptive randomization (experimental module), Traditional trials with multiple objectives (experimental module). Traditional trials with cluster-randomized designs (experimental module).

Last updated 2 years ago

cpp

3.79 score 20 stars 31 scripts 424 downloads

MCPModPack - Simulation-Based Design and Analysis of Dose-Finding Trials

An efficient implementation of the MCPMod (Multiple Comparisons and Modeling) method to support a simulation-based design and analysis of dose-finding trials with normally distributed, binary and count endpoints (Bretz et al. (2005) <doi:10.1111/j.1541-0420.2005.00344.x>).

Last updated 2 years ago

cpp

2.00 score 1 stars 1 scripts 369 downloads